Ron Kirshner vs.Flash Essay Example | Topics and Well Written Essays - 1000 words - 1

Ron Kirshner vs.Flash - Essay Example of the Bozapalooza but he told Kirshner that an SnS reunion concert was out of the question due to differences between Flash and fellow SnS member Axl. Flash made it clear that because of past arguments he would not perform on stage with Axl. These negotiations occurred in September. Flash also indicated that he would go to Thailand and therefore could not be reached for the time being. Flash informed Kirshner that he would be gone from Sept 23 to October 22; during that period he would be incommunicado. Kirshner sent a letter on September 21, via regular mail, stipulating their agreements. It arrived September 24 or after Flash had already left for his overseas trip. When Flash returned from his trip he was surprised to learn that he would be performing with Axl at the Bozapalooza against his express wishes. Kirshner informed him that because Flash could not be reached, he went ahead and booked the concert with Axl. Hence Flash wants to know if he is legally obligated to perform at the concert. A contract requires a meeting of minds between the parties involved. There must be an offer from one party and an acceptance of that offer on the part of the other party. In the present case, there appears to be a reciprocal obligation between Kirshner and Flash. There was an offer by Kirshner for Flash to perform at the Bozapalooza in exchange for a sum certain in money. Kirshner, as promissor, showed a willingness to be legally bound by the terms he specified in a way that would lead a reasonable person in the position of Flash to understand that an acceptance is being sought and, if made, would result in an enforceable contract. Now, an important matter to consider is what the stipulation of the contract was. On September 1, Ron made an initial offer involving an SnS reunion concert at Bozapalooza. The response of Flash was a counter-offer stating that while he was willing to perform at Bozapalooza, he would not perform with Axl. Negotiations resumed on September

How I Undertook the Conduct of Research Essay Example | Topics and Well Written Essays - 4000 words

How I Undertook the Conduct of Research - Essay Example Where did you start with your research? b. How and why did you approach the various aspects of your work? c. How, why and where you found things? d. Why were some things useful, and why were others not? Where did you start your research? The research done in order to write the research paper was conducted with a view to analyse existing legal rules and jurisprudence on the law on assisted dying. I started my research by first reflecting and asking myself what I wanted to find out and how I wanted to proceed. Did I have a specific opinion on whether or not the law should be reformed and then find justification for such an opinion, or did I want my own opinions to be shaped by the data that I would come across in the course of my own research? The first thing I did was to acknowledge that I had a specific and definite opinion on the issue of assisted dying and it was that I believed the law was in great need of reformHowever, I also wanted to ensure that I started as objectively as pos sible, and thus it was important for me to get an accurate definition of assisted suicide. For this, I wanted not grey literature or advocacy literature, but something scientific and credible. Thus I relied on a book entitled â€Å"Medical Law and Ethics†. I found that the definition of euthanasia, or assisted dying is, the act of consciously assisting someone’s death in order to relieve that person of suffering as a result of terminal illness1. I also found that this can be broken down into even more classifications, such as passive and active, as well as voluntary and involuntary. After knowing what the definition of euthanasia, I then focused on finding what the law presently states on the subject matter. For this, it was of course helpful to not only look at the appropriate statutes and criminal code, but also to look at what eminent jurists were saying on the subject matter. It quickly became clear in the course of my research that while neighbouring countries lik e The Netherlands and Belgium – both in close proximity to the United Kingdom in more ways than geography -- have allowed euthanasia and in fact, many citizens of the UK and around the world have made the tip to these two countries to have assisted suicide performed on them, it is still illegal in our jurisdiction. How and why did you approach the various aspects of your work? Because I did not want to just focus on a general reform call, I wanted to be specific to a particular bill. To this end, I focused on the Assisted Suicide bill by Lord Joffe, which was priorly defeated in the House of Lords. As I stated in my reform paper, the bill, if enacted into law, would allow terminally ill patients to seek drugs from their doctors that would end their lives. The benefits of the act, if passed, will only be for those who have been medically diagnosed to live for six months, who are suffering from unbearable pain, and who are psychologically of sound mind and not depressed. I chos e this particular reform bill because it is by and large the most debated upon and controversial bill with respect to euthanasia and the debates on the merits of this bill have not abated even after its defeat. This research primarily relied on doctrinal methods. Paul Chynoweth defines the Doctrinal Legal Research as follows:

See my attchment Essay Example | Topics and Well Written Essays - 1750 words

See my attchment - Essay Example From decades this procedure was being followed in hospitals and Medicare centers which was a time consuming and hectic work. Healthcare Information database was thus the need and necessity of time according to the prevalent healthcare scenario in the country. To take care about patient’s health record and doctor patient fast interaction; National Health Services (NHS) took care the responsibility of introducing Health Information Technology (HIT) into hospitals and Medicare centers of United Kingdom. The key reasons of implementing this mega setup was to get rid of hardcopies of patient records, fasten the process, serve the patients well and ease the doctors as they would have previous health record of patients available all the time. United Kingdom government took immense steps for the implementation of this system by providing necessary funds. The purpose of this paper is to have a clear cut understanding of health information technology invasion, implementation, processes and position in United Kingdom Medicare setup. Discussion of the response from government in the adaptation of this idea and reaction attained from the relevant institutions etc. Providing best healthcare services is the intention of United Kingdom government and for this they take essential necessary steps. The progression of technology gave opportunity to humans to maintain healthcare records of patients online on an online portal. The involvement of United Kingdom government was massive in this regard thus National health Services was given the task to implant state of the art healthcare services. National health Services proceeded in taking significant steps about this matter and introduced Healthcare Information Technology (HIT) in the year 2002. The aim was primarily to maintain a centralize database of patients so that it would ease processes (Jha, Doolan & Scott, 2008‎, p.

Ron Kirshner vs.Flash Essay Example | Topics and Well Written Essays - 1000 words - 1

Ron Kirshner vs.Flash - Essay Example of the Bozapalooza but he told Kirshner that an SnS reunion concert was out of the question due to differences between Flash and fellow SnS member Axl. Flash made it clear that because of past arguments he would not perform on stage with Axl. These negotiations occurred in September. Flash also indicated that he would go to Thailand and therefore could not be reached for the time being. Flash informed Kirshner that he would be gone from Sept 23 to October 22; during that period he would be incommunicado. Kirshner sent a letter on September 21, via regular mail, stipulating their agreements. It arrived September 24 or after Flash had already left for his overseas trip. When Flash returned from his trip he was surprised to learn that he would be performing with Axl at the Bozapalooza against his express wishes. Kirshner informed him that because Flash could not be reached, he went ahead and booked the concert with Axl. Hence Flash wants to know if he is legally obligated to perform at the concert. A contract requires a meeting of minds between the parties involved. There must be an offer from one party and an acceptance of that offer on the part of the other party. In the present case, there appears to be a reciprocal obligation between Kirshner and Flash. There was an offer by Kirshner for Flash to perform at the Bozapalooza in exchange for a sum certain in money. Kirshner, as promissor, showed a willingness to be legally bound by the terms he specified in a way that would lead a reasonable person in the position of Flash to understand that an acceptance is being sought and, if made, would result in an enforceable contract. Now, an important matter to consider is what the stipulation of the contract was. On September 1, Ron made an initial offer involving an SnS reunion concert at Bozapalooza. The response of Flash was a counter-offer stating that while he was willing to perform at Bozapalooza, he would not perform with Axl. Negotiations resumed on September

See my attchment Essay Example | Topics and Well Written Essays - 1750 words

See my attchment - Essay Example From decades this procedure was being followed in hospitals and Medicare centers which was a time consuming and hectic work. Healthcare Information database was thus the need and necessity of time according to the prevalent healthcare scenario in the country. To take care about patient’s health record and doctor patient fast interaction; National Health Services (NHS) took care the responsibility of introducing Health Information Technology (HIT) into hospitals and Medicare centers of United Kingdom. The key reasons of implementing this mega setup was to get rid of hardcopies of patient records, fasten the process, serve the patients well and ease the doctors as they would have previous health record of patients available all the time. United Kingdom government took immense steps for the implementation of this system by providing necessary funds. The purpose of this paper is to have a clear cut understanding of health information technology invasion, implementation, processes and position in United Kingdom Medicare setup. Discussion of the response from government in the adaptation of this idea and reaction attained from the relevant institutions etc. Providing best healthcare services is the intention of United Kingdom government and for this they take essential necessary steps. The progression of technology gave opportunity to humans to maintain healthcare records of patients online on an online portal. The involvement of United Kingdom government was massive in this regard thus National health Services was given the task to implant state of the art healthcare services. National health Services proceeded in taking significant steps about this matter and introduced Healthcare Information Technology (HIT) in the year 2002. The aim was primarily to maintain a centralize database of patients so that it would ease processes (Jha, Doolan & Scott, 2008‎, p.

The audience can sympathise Essay Example for Free

The audience can sympathise Essay Arthur Miller wrote A View from the Bridge as a modern version of a Greek tragedy, therefore, Eddies death at the end of Act Two should be tragic. The audience have to feel pity, or pathos, towards Eddie when he dies to make the play a successful tragedy. According to 1.Aristotles definition of a tragic hero, the hero should be noble and of high status; he should have a flaw, or hamartia, which should lead to his tragic ending; his punishment should seem to be harsher than his crime; and he should realise that his flaw has led to his tragedy. By making his play a modern version of a Greek tragedy, Miller uses the character of Alfieri, his description of Eddie as a likeable and respected man and an extreme and violent death in the arms of his wife to make the audience sympathise with him and to make him a tragic hero. Throughout the play, Miller gives his audience many reasons to respect and admire Eddie. Although there is too much love (p. 48) for his niece, it is also obvious that he is very protective over Catherine and genuinely cares about her. Eddie and his wife have taken Catherine in and have given her a loving and caring home to live in. Also, Eddie seems popular within his community, is liked by Louis and Mike and is described by Alfieri as good a man as he had to be in a life that was hard and even. (p. 26) Eddie is respected both in the house, because he is head of the household, and in the community. This shows that he is actually a noble person, with high status in the Italian-American community. He is the only person in the family who works; he is the provider for the family. Miller shows how hardworking Eddie is because he has to earn a living for his whole family and despite the mistakes he makes, both Catherine and Beatrice love him until he dies at the end of the play. Many may feel sorry for Eddie even without the chorus, Alfieri, being there to lead the audience though the play. In the beginning of the play, when Beatrice tells Eddie, Shes got a job. (p. 18), Eddie seems shocked and says to Catherine Its not wonderfulYou cant take no job. Why didnt you ask me before you take a job? (p. 18). This quote shows the audience that Eddie disapproves of this and does not want his niece to leave him, even though Beatrice and Catherine had wanted Eddie to be happy about this. When Beatrice tells Eddie that Catherine will earn fifty dollars a week (p. 18), Eddie is taken aback and his jealousy of Catherine earning more than he does becomes more and more obvious throughout the conversation. Later on in the discussion, Eddie says I want you to be in a nice office. Maybe a lawyers office someplace in New York in one of them nice buildings. (p. 19). This contradicts what Alfieri says in his introduction to the play In this neighbourhood to meet a lawyer or a priest on the street is unlucky. Were only thought of in connexion with disasters, and theyd rather not get too close. (p. 11). Later on in the play, when Catherine fell in love with Eddie, Eddie gets even more envious and angry. In his conversation with Catherine, he says He [Rodolpho] marries you hes go the right to be an American citizenThe guy is lookin for his break, thats all hes lookin for. (p. 41). This shows how angry Eddie is at the fact that Catherine likes Rodolpho, and not him. Miller helps the audience sympathise with Eddie in this scene by making Catherine trust Rodolpho instead of Eddie. To a modern audience, there may be some features in Eddie that are hard not to dislike. His flaw involves love for a girl he has raised as if she was his own daughter, a terrible taboo. Also, Eddie is a parental figure who seems to expect women to do domestic work for him. Tragic heroes usually recognise their own mistakes. In Greek tragedies, this is the moment in a play when the tragic hero appreciates their own weakness and their own responsibility. However, throughout the play, Eddie does not admit to himself the truth about loving Catherine. Although Beatrice tries to make him face this truth by saying You want somethin else, Eddie and you can never have her (p. 83), Eddie seems truly shocked and grasps his head as though it would burst (p. 83). All throughout the play, Eddie never really seems capable of facing what he feels or admitting his responsibility. Even in the end of the play, Eddie says, Marco, tell them what a liar you are! (p. 84) To try and prevent the audience from making harsh judgements of Eddie, Miller uses Alfieri as a type of chorus in the play. In Greek tragedies, the chorus are observers who judge actions fairly. They help the audience to consider the elements of the play. As the chorus, Alfieri sympathises with Eddie, along with the audience. He expresses his feelings and thoughts to the audience about what happens throughout the play and provides judgement. In the play, Alfieri suggests that it is normal and human to sin. He also states that many people have hidden guilty secrets but there is something beautiful in a man whose sins are so public and so clear that he becomes wholly known (p. 85). Before Eddie calls the immigration department, Alfieri warns him that even those who understand will turn against you (p. 67), which shows that Eddies weakness is not special, but that other people still will judge him. Then, with Eddie dying on stage, Alfieri ends the play by saying, I confess that something perversely pure calls to me from his [Eddies] memoryfor he allowed himself to be wholly known and for that I think I will love him (p. 85) In other words, since we all have guilty secrets but manage to keep them hidden inside, there is something quite pure in a person whose guilty secrets are not unknown. An oxymoron Miller used, perversely pure (p. 85), shows that Alfieri wants us to think about our own weaknesses and not judge Eddie too harshly. Another common feature of Greek tragedy is that the death should seem predictable, and that it cannot be stopped. Miller uses Alfieri to suggest this to the audience, as if it is out of control of the character. Right from the beginning, Miller makes it obvious that Eddie would die in the end. Alfieri keeps giving clues to the audience about Eddie being destined to die, saying he felt powerless and watched it run its bloody course. (p. 12) Another quote from Alfieri is, I knew where he [Eddie] was heading for, I knew where he was going to end. (p. 50) These quotes make us feel more pity for Eddie because, even when he seems happy and loving, we still know he is heading towards a bloody (p. 12) end. Miller successfully makes Eddie a sympathetic character by making him fit the tragic hero he is supposed to be. The audience goes from admiring Eddie to getting to know his terrible guilty secret. Through the whole play we get the unescapable feeling that he is heading towards his bloody end and that it is his guilty secret that will cause it. Although for some modern theatre audiences, Eddie may seem to be an old-fashioned man and although he never really admits his own faults, Miller uses Alfieris character to make sure we can still feel the intended pity. I think this is Millers greatest achievement in this play, reminding us that we are all human, guilty in some ways, and that we should feel sorry for ourselves and Eddie for that.

Serotonin Function and Mechanism of Antidepressant Action

Serotonin Function and Mechanism of Antidepressant Action Neurotransmitters are chemicals located and released in the brain to allow an impulse from one nerve cell to pass to another nerve cell. There are approximately 50 neurotransmitters identified. There are billions of nerve cells located in the brain, which do not directly touch each other. Nerve cells communicate messages by secreting neurotransmitters. Neurotransmitters can excite or inhibit neurons (nerve cells). Some common neurotransmitters are acetylcholine, norepinephrine, dopamine, serotonin and gamma aminobutyric acid (GABA). Serotonin is a monoamine neurotransmitter. It is synthesized, from the amino acid L-tryptophan, in brain neurons and stored in vesicles. Serotonin is found in three main areas of the body: the intestinal wall; large constricted blood vessels; and the central nervous system. The most widely studied effects have been those on the central nervous system. The functions of serotonin are numerous and appear to involve control of appetite, sleep, memory and learning, temperature regulation, mood, behavior (including sexual and hallucinogenic behavior), cardiovascular function, muscle contraction, endocrine regulation, and depression. It is a well-known contributor to feelings of well-being; therefore it is also known as a happiness hormone despite not being a hormone. Serotonin is an inhibitory neurotransmitter which complements excitatory sympathetic systems like adrenaline and dopamine in the Central Nervous System. The physiological activity of serotonin starts from the brainstem in groups of brain cells called Raphe nucleus. Serotonin brain cells then spread to various regions of the central nervous system by branching out throughout the brain. History In 1935, Italian Vittorio Erspamer showed that an extract from enterochromaffin cells made intestines contract. Some believed it contained adrenaline, but two years later Erspamer was able to show that it was a previously unknown amine, which he named enteramine.[4] In 1948, Maurice M. Rapport, Arda Green, and Irvine Page of the Cleveland Clinic discovered a vasoconstrictor substance in blood serum, and since it was a serum agent affecting vascular tone, they named it serotonin. In 1952 it was shown that enteramine was the same substance as serotonin, and as the broad range of physiological roles were elucidated, the abbreviation 5HT of the proper chemical name 5-hydroxytryptamine became the preferred name in the pharmacological field. Mechanism of action The activity of serotonin arises in the brainstem from clusters of neurons known as the raphe nucleus. From the brain, serotonin neurons extend to virtually all parts of the central nervous system making the branching of the serotonin network the most expansive neurochemical system in the brain. The importance of this network becomes apparent when considering each serotonin neuron exerts an influence over as many as 500,000 target neurons. Due to the widespread distribution of serotonin in the nervous system, it is not surprising that this neurotransmitter can be linked to many types of behavior. Of the chemical neurotransmitter substances, serotonin is perhaps the most implicated in the treatment of various disorders, including anxiety, depression, obsessive-compulsive disorder, schizophrenia, stroke, obesity, pain, hypertension, vascular disorders, migraine, and nausea. A major factor in the understanding of the role of 5-HT in these disorders is the recent rapid advance made in understanding the physiological role of various serotonin receptor subtypes. There are at least four populations of receptors for serotonin: 5-HT1, 5-HT2, 5-HT3, and 5-HT4. The physiological function of each receptor subtype has not been established and is currently the subject of intensive investigation. Effects as a neurotransmitter Most neurotransmitters are released from tiny synaptic terminal buttons at the ends of nerve cells, but serotonin appears to be different. It is instead released freely from serotonergic varicosities into the general neuronal space, diffusing over a much larger area to activate the 5-HT receptors of nearby neurons. This reuptake can be disrupted by agents like MDMA, cocaine, tricyclic antidepressants (TCAs), and selective serotonin reuptake inhibitors (SSRIs). The overall action of serotonin is very complex and not entirely understood. Peripheral effects Cardiovascular action The cardiovascular effects of serotonin are complex. They are variable depending on the dose injected, experimental conditions, animal species and vascular state. Action on vessels: Serotonin induces either a vasoconstriction by 5-HT2 effect, in particular of renal vessels, or a vasodilation. Serotonin constricts veins and seems to induce venous thromboses and promotes platelet aggregating effect. It increases capillary permeability. Action on heart: Serotonin has a positive chronotropic action by 5-HT4 receptor stimulation and could take part in the genesis of certain rhythm disorders. It has a positive inotropic effect. Action on blood pressure: It is complex, according to experimental conditions, serotonin gives either hypotension, or hypertension, or no modification. Action on smooth muscles Serotonin induces contractions of intestine, bronchi and uterus. Digestive effects: Serotonin increases intestinal motility, probably by stimulation of 5-HT4 and 5-HT3 receptors: in human beings, injected by intravenous route, it increases duodenum and small intestine motility. This effect explains diarrhea observed in patients with carcinoid syndrome. Bronchial effects: Serotonin has a bronchoconstrictive action and a serotonin aerosol induces dyspnea (difficult or labored respiration). Uterus effect: Serotonin induces contractions of the uterus. Other actions Researchers have also found evidence that serotonin may play a role in regulating milk production in the breast, and that a defect within the serotonin network may be one underlying cause of SIDS (sudden infant death syndrome). Central effects Serotonin is involved in the regulation of sleep, mood (antidepressant action), temperature, appetite (appetite suppressant effect). Overstimulation of 5-HT2 receptors could induce productive and negative symptoms of psychotic disorders. LSD or lysergide, agonist of 5-HT2 receptors and also of D1 and D2 dopaminergic receptors, has hallucinogenic properties. Serotonin, thanks to its various types of presynaptic and postsynaptic receptors, modulates the activity of other transmitters. It plays a determining part in adaptation. Effects of Excess or Low Serotonin Serotonin is involved in allergic and inflammatory symptoms and in certain diseases: Carcinoid syndrome: The carcinoid syndrome is caused by metastatic tumors of enterochromaffin cells of the digestive tract which secrete various compounds, in particular a great quantity of serotonin. It is characterized by diarrhea, flushes (accesses of cutaneous vasodilation followed by a vasoconstriction), dyspnea and sometimes a damage to cardiac valves. The biological diagnosis of these tumors is based on the increase in serotonin concentration in blood and on the excretion of abnormal amounts of 5-hydroxy-indolacetic acid, 5-HIAA, in urines. Migraine: Migraine is a disease characterized by repeated accesses of headache in which vasomotor phenomena and serotonin play a determining part. In the first prodromic phase, there is a vasoconstriction, and in the second painful phase, a vasodilation. This vasodilation is reduced by vasoconstrictive drugs. Myocardial ischemia: Serotonin released from platelets seems to worsen the myocardial ischemia by vasoconstriction. Hallucinations occur due to increased levels of Serotonin. Generalized anxiety disorder People with generalized anxiety disorder (GAD) experience excessive worry that causes problems at work and in the maintenance of daily responsibilities. Evidence suggests that GAD involves several neurotransmitter systems in the brain, including norepinephrine and serotonin. Deficiencies or excessive intake of certain dietary minerals and vitamins can disrupt the level of serotonin, causing disruptions in the production or reuptake processes surrounding serotonin. Several drugs that affect the serotonin system Several classes of drugs target the 5-HT system, including some antidepressants, antipsychotics, anxiolytics, antiemetics, and antimigraine drugs, as well as the psychedelic drugs and empathogens. When Serotonin is low, certain problems with concentration and attention can be experienced. People become scatterbrained and poorly organized. It takes longer to do things because of poor planning. When Serotonin is moderately low, the following symptoms and behaviours have been observed: Chronic fatigue. Despite sleeping extra hours and naps, fatigue remains. There is a sense of being worn out Sleep disturbance. Appetite disturbance is present, usually in two types. There is a loss of appetite and subsequent weight loss or a craving for sweets and carbohydrates when the brain is trying to make more Serotonin. Total loss of sexual interest is present. In fact, there is loss of interest in everything, including those activities and interests that have been enjoyed in the past. Social withdrawal is common not answering the phone, rarely leaving the house/apartment, stop calling friends and family, and withdrawal from social events. Emotional sadness and frequent crying spells are common. Self-esteem and self-confidence are low. Body sensations, due to Serotonins role as a body regulator, include hot flushes and temperature changes, headaches, and stomach distress. Clinical Depression This is perhaps the most common mental health problem encountered in practice. One in four adults will experience clinical depression within their lifetime. Serotonin acts as an important feel-good neurotransmitter, sending signals that an individual is relaxed and happy. In the absence of serotonin, patients feel sad and unwell and may even experience fear, anxiety and physical discomfort. serotonin acts as an important feel-good neurotransmitter, sending signals that an individual is relaxed and happy. In the absence of serotonin, patients feel sad and unwell and may even experience fear, anxiety and physical discomfort. Treatment for depression, as might be expected, involves increasing levels of Serotonin in the brain. Since the mid-eighties, medications have been available that attempt to specifically target and increase Serotonin. Known as Selective Serotonin Reuptake Inhibitors (SSRIs), these medications such as Prozac, Zoloft, and Paxil are felt to work by making more Serotonin available in the brain. Like all neurotransmitters, we can have too much Serotonin. Obsessive-Compulsive Disorder The American Academy of Family Physicians explains that one of the disorders categorized as a serotonin deficiency-related illness is obsessive-compulsive disorder. In this psychiatric condition, patients feel obsessed with certain issues, like cleanliness or order, and are therefore compelled to engage in what they perceive as related behaviors, including rigorous and repetitive cleaning or hand washing. Researchers have determined that low levels of serotonin in the brain are responsible for many cases of obsessive-compulsive disorder, and physicians prescribe pharmaceuticals that help increase brain levels of serotonin. These drugs help reduce or relieve symptoms entirely, allowing individuals with obsessive-compulsive disorder to live normal lives. Serotonin Syndrome While elevated levels of Serotonin produce a sense of well-being, bliss, and oneness with the universe too much Serotonin can produce a life-threatening condition known as Serotonin Syndrome (SS).Likely to occur by accident by combining two Serotonin-increasing medications or substances. These are some of its symptoms: Cognitive mental confusion, hypomania, agitation, headache, coma Autonomic shivering, sweating, fever, hypertension, tachycardia, nausea, diarrhea Somatic myoclonus/clonus (muscle twitching), hyperreflexia, tremor Emergency medical treatment is required, utilizing medications that neutralize or block the action of Serotonin as the treatment for Serotonin Syndrome (SS). Discontinuation syndrome Antidepressants such as SSRIs have some dependence producing effects, most notably a withdrawal syndrome. Their dependence producing properties (depending on the antidepressant) may not be as significant as other psychotropic drugs such as benzodiazepines, however, withdrawal symptoms nonetheless may be quite severe and even debilitating. SSRIs have little abuse potential, but discontinuation can produce disturbing withdrawal symptoms that may not be able to be distinguished from a reoccurrence of the original illness: Sexual side effects Cardiac side effects Suicide risk Post SSRI sexual dysfunction Aggression Permanent nuerophysiological changes Persistent pulmonary hypertension Bleeding tendencies Applications of Serotonin SSRIs Selective serotonin reuptake inhibitors (SSRIs) are commonly used as first-line therapy to treat mood disorders due to their demonstrated efficacy, safety, and tolerability profiles. SSRIs may play an intricate role in treating hormone-mediated disorders that disturb the quality of life for women. Selected uses of SSRIs, specifically in the treatment of hot flashes, premenstrual dysphoric disorder, and postpartum depression, are explored in this article. Data from several studies support the use of SSRIs in these conditions, and therefore, these agents have the potential to significantly improve mood, cognitive function, physical symptoms, and social functioning in patients with these disorders. In addition, SSRIs may prove to be viable alternatives to current therapies that may be contraindicated, poorly tolerated, or lack efficacy in patients with these disorders. Post Traumatic Stress Syndrome PTSD is an anxiety disorder affecting individuals who have been exposed to a disastrous event, which may have threatened their lives or included witnessing tragic harm being afflicted. This disorder is most often related to individuals who have experienced combat. Patients are treated with an SSRI-Selective Serotonin Receptacle Inhibitors that have a calming effect on the body. The result for the patient is a calming effect on the body and reduction in the feeling of anxiety and aggression. Fibromyalagia Fibromyalgia is a disorder characterized by widespread pain of the muscles and tendons accompanied by varied tender points all over the body and general fatigue. Fibromyalgia affects more women than men and occurs in 2 percent of the population in the United States. As serotonin is a pain-fighting hormone, it is frequently used to treat fibromyalgia. Many medical professionals agree fibromyalgia is caused by low levels of serotonin. Besides taking supplements, serotonin can be taken from natural sources of tryptophan. Tryptophan is an amino acid that aids in the bodys production of serotonin and is found in soy, turkey, chicken, halibut, beans and cheddar cheese. General Stress Serotonins mood regulating neurotransmitters help alleviate stress in sufferers. People suffering from chronic stress benefit from supplementing their regular diet with serotonin, or tryptophan to increase its production. In some cases, using lavender can induce feelings of calm and happiness. Known as a feel good hormone, serotonin is actually lowered by high levels of stress and therefore must be added back. Ways to increase serotonin levels: Eat healthy Free Range Turkey Tryptophan is an essential amino acid that is present, in different amounts, in all protein foods. This amino acid is the building block for the neurotransmitter serotonin. Flaxseed/ Flaxseed oil As well as being great for fat loss, flaxseeds are great foods that raise serotonin levels because they contain both tryptophan and high levels of omega 3 fatty acids. 60 percent of the brain is made of structural fats, and omega 3 fatty acids make up a large proportion of brain nerve cells. Wild Fish and Sea food = Fatty fish like wild salmon, sardines and herring are rich in oils containing the essential fats EPA and DHA. Both of these long chain fats have been shown in trials both to smooth the mood swings of bipolar disorder and to ease regular depression. Whey protein = Whey protein has gained a greater and greater reputation as a super-food over recent years. Whey has been shown to regulate appetite, improve insulin sensitivity and blood sugar levels, bolster the immune system and has been shown to be the ideal protein source to use around workout time. Bananas High quality Eggs Sour Cherries Free Range Beef Dark Chocolate Cocoa is well known to increase serotonin levels in the brain the trick is not to eat so much that you crash a few hours later. Similarly most chocolate is clearly high in sugar and will spike blood sugar levels causing serotonin levels to plummet when your blood sugar crashes.